Professor of Microbiology
University of Piemonte Orientale
Dept. of Translational Medicine, Italy
Marisa Gariglio MD, PhD, is Professor of Medical Microbiology at the Medical School of Novara, University of Piedmont Region, Novara-Italy. She received her degree in Biology in 1984 and her Medical degree in 1990 from the University of Turin-Italy, where she also completed her PhD program in Immunology and Microbiology. After post-doctoral training at the Department of Molecular Biology "Hoffmann La Roche" (Basel-Switzerland) studying transcriptional regulation of interferon-inducible genes, she joined the Novara Medical School in 1995 as Assistant Professor. Since 2001, she is full professor and P.I. of the laboratory of Molecular Virology. Her laboratory has interests in the pathogenesis, molecular genetics and biochemistry of human papillomaviruses (HPV). Emphasis has been placed on understanding betaHPV-epithelial keratinocyte interactions in naturally occurring patient lesions, such as skin cancer developing in immunosuppressed patients (including organ transplant recipients) and patients suffering from primary immunodeficiency (including Epidermodysplasia verruciformis), and on developing experimental model skin systems (organotypic raft cultures and transgenic mice) that closely reflect these events. Her background is also including the interferon system, particularly the role of the DNA sensor IFI16 in intrinsic antiviral immunity against cytomegalovirus and papillomavirus.